Transition metal-α-amino acid complexes with antibiotic activity against Mycobacterium spp.
نویسندگان
چکیده
Synthetic iridium-, rhodium-, and ruthenium-amino acid complexes with hydrophobic l-amino acids have antibiotic activity against Mycobacterium spp., including Mycobacterium bovis BCG and the rapidly growing species Mycobacterium abscessus and Mycobacterium chelonae. Concentrations of transition metal-amino acid complexes demonstrating hemolysis or cytotoxicity were 10- to 25-fold higher than were the MICs.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 57 7 شماره
صفحات -
تاریخ انتشار 2013